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 Wysłany: Wto 22:12, 10 Maj 2011 Temat postu: Abercrombie,Thrombolysis in acute ischemic stroke |
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Thrombolysis in acute ischemic stroke treatment progress
[Key words] stroke thrombolysis Health Network News:
185mmHg, or diastolic blood pressure> 110mmHg; (7) septic embolism; ( the most
30 days have AMI; (9) coagulation disorder.
Treatment: Dose 0.9mg/kg (maximum dose 90mg), 10% of total intravenous, and the remaining doses of intravenous 60m
in above.
4 arterial thrombolytic therapy
Local arterial thrombolysis is to a micro-catheter into the blocked artery emboli before or after, and then injected into
Thrombolytic drugs. Widely used in the world of this therapy is based on two randomized trials and a large number of case reports
. In the past, urokinase is the most common study drug,[link widoczny dla zalogowanych], and recently, t-PA and urokinase are the main before the study drug
. About 40% of patients after complete arterial thrombolysis after arterial recanalization, about 35% of patients after thrombolytic therapy
Partial recanalization after [17]. Arterial thrombolysis thrombolytic recanalization rates than the higher rate of reperfusion [18].
Two large studies in the larger one, the PROACT Ⅱ trials for patients is the result of cerebral angiography
Determined middle cerebral artery occlusion or branch initial segment of [3]. 12,[link widoczny dla zalogowanych],323 cases of patients through the screening, 474
Patients do angiography, and finally 180 patients were enrolled; 121 cases before the patients received local arterial urokinase mediated
Into the low-dose heparin therapy and intravenous therapy. 2h 67% of patients after partial or complete recovery,[link widoczny dla zalogowanych],[link widoczny dla zalogowanych], but the cerebral hemorrhage
The occurrence rate of 10%.
Arterial thrombolysis interventional techniques: Indications: (1) acute sudden persistent neurological damage, manifested as brain
Artery occlusion; (2) onset time within 12h; (3) CT ruled out intracerebral hemorrhage or cerebral vascular malformation; (4), cerebral blood
Control angiography shows emboli is soluble. Excluded cases: (1) patients is a small vessel occlusion; (2) CT has a show
Blood; (3) suspected tumor, infection of the patient; (4) 48h before the onset of anticoagulation therapy of patients used; (5) elimination
Resistance ulcers; (6) 10 days who had major surgery; (7), systolic blood pressure> 220mmHg, or diastolic blood pressure> 110mmHg.
Treatment Methods: DSA interventional, interventional catheter through the femoral artery into the aortic arch the body, and then enter the
Side blocked carotid artery,[link widoczny dla zalogowanych], into the middle cerebral artery, the urokinase into the thrombus.
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