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Wysłany: Pią 15:22, 11 Mar 2011
Temat postu: adidas scarpe ino fui qqt ths
Rat tissues trisphosphate receptor subtype gene expression
Composition of the end of a transmembrane segment. 1t the molecular structure is divided into three functional areas, and endoplasmic reticulum transmembrane segment within the channel lumen area, the cytoplasm of the R binding domain,
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, the middle part of the regulatory regions, including the phosphorylation site and ATP binding site. Combined with the specific site can cause c channel opening, PKA phosphorylation of IP, 1t adjustable mediated c mobilization. This establishment of a sensitive,
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, simple and specific detection of semi-quantitative ItT-pcR Mary RmRNA method. Ct person with a PdCTP RT-PCR amplification of mixed, and the specific bands of radioactive counts and optical density scanning, can be used to further compare the tissue expression of various subtypes of rnRNA way. The product of automated sequencing of this article PcR reported results consistent with the purpose of DNA sequences, which show that the establishment of the lit-PCJI system is reliable functional RmRNA ~ species determination. Detection of the cerebellum, heart and VSNC in the expression of I-IP31traRNA. Amplified fragments were found in the corresponding 525bp and 405bp, that in the cerebellum there is an I-RmRNA composed of nucleotide sequences from the 120bp insert. MRNA transcription level of the cut in different ways, forming two fragments sI and s Ⅱ】. SU fork further divided into A, B and C3 fragments which constitute a sub-s Ⅱ, SUB A, SII (Re) I and SU (Argo). SU exists only in the mature nervous system, s Ⅱ a widely expressed in peripheral tissues of S Ⅱ series edge by a 120bp nucleotide sequences of the inserted fragments,
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, the two cAMP in the regulation region of the kinase phosphorylation dependent areas such as bit sequences , thus forming the role of PKA substrate. I-cerebellar and liver cells have different Km values of R and R induced PKC phosphorylation function of two opposing changes in the B-mediated cerebellar inhibition of calcium mobilization of a small body of c,
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, but for B-mediated liver cell storage calcium release. R Ⅲ type is inconsistent with the reported results, the reason is not clear whether a new way to further study the shear trisphosphate receptor expression in the cardiovascular system has important pathophysiological significance of J,
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, such as heart failure R Abnormal expression of changes in myocardial contractility may be one of the mechanisms j. BR in the nervous system signal transduction process also played a key role. The results of this research in this area provided a strong foundation.
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