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<table border="0" cellpadding="3" cellspacing="1" width="100%" class="forumline"> <tr> <th class="thCornerL" width="22%" height="26">Autor</th> <th class="thCornerR">Wiadomość</th> </tr> <tr> <td width="22%" align="left" valign="top" class="row1"><span class="name"><a name=""></a><b>op41oppa</b></span></td> <td class="row1" height="28" valign="top"><table width="100%" border="0" cellspacing="0" cellpadding="0"> <tr> <td width="100%"><img src="http://picsrv.fora.pl/xeon/images/icon_minipost.gif" width="12" height="9" alt="Post" title="Post" border="0" /><span class="postdetails">Wysłany: Pon 6:49, 14 Mar 2011<span class="gen"> </span> Temat postu: sodium pumps</span></td> </tr> <tr> <td colspan="2"><hr /></td> </tr> <tr> <td colspan="2"><span class="postbody">structure and function <br />the na+-k+-atpase is composed of two subunits. the alpha subunit (~113 kd) is the action hero of the pair - it binds atp and both sodium and potassium ions, and contains the phosphorylation site. the smaller beta subunit (~35 kda glycoprotein) is absolutely necessary for activity of the complex. it appears to be critical in facilitating the plasma membrane localization and activation of the alpha subunit. <br />several isoforms of both alpha and beta subunits have been identified, but aside from kinetic characterizations and tissue distribution, little is known regarding their differential physiologic importance. <br /> <br />uncertainties remain in describing the structure of this molecule, but based on primary amino acid sequence,<a href="http://Black-and-white-radio.de/smf/index.php?topic=28563.msg30662#msg30662" target="_blank" class="postlink">American Turbine Pump American Turbine Pump</a>, it is thought to possess 8 or 10 transmembrane domains. considerable information is available to define the amino acids involved in atp and cation binding. <br /> <br />cation transport occurs in a cycle of conformational changes apparently triggered by phosphorylation of the <a href="http://www.sail-trade.com/" target="_blank" class="postlink">pump</a>. as currently understood,<a href="http://nmaplateau.org/forum/index.php?topic=125511.msg159667#msg159667" target="_blank" class="postlink">South Carolina Manufacturers Alliance</a>,<a href="http://www.sail-trade.com/" target="_blank" class="postlink">HAND PALLET TRUCK</a>,<a href="http://rintasyopayhdistys.agileus.fi/foorumi/viewtopic.php?p=61899#61899" target="_blank" class="postlink">China Manufacturer and Manufacturer Directory from</a>, the sequence of events can be summarized as follows:</span></td> </tr> </table></td> </tr> <tr> <td colspan="2" height="1" class="spaceRow"><img src="http://picsrv.fora.pl/xeon/images/spacer.gif" alt="" width="1" height="1" /></td> </tr> </table>
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