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lin22307
Wysłany: Śro 8:14, 23 Mar 2011
Temat postu: nike high heels Serum GPDA-F and GGT-Ⅱ combined d
Serum GPDA-F and GGT-Ⅱ combined detection in the diagnosis of primary liver cancer
Correlation between the PHC has some of the AFP-negative clinical value in the positive rate of AFP-negative PHC were 75.0% and 536%. GPDA as a hydrolysis of glycyl-proline 0, a dipeptide naphthyl naphthylamine lactamases. Industry research has shown, liver and gallbladder disease often elevated serum GPDA total activity,
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, especially in PHC is obvious, the positive rate of about 50% to 60%. low. In recent years, our department to establish and improve the separation of serum GPDA isozyme detection method. separated from the serum of patients with PHC out a correlation between liver isoenzyme zone GPDA-GPDA-F. Clinical studies have shown that, GPDA-F The sensitivity and specificity of diagnosis of PHC were significantly higher than the total live GPDA l of the study, GPDA-F in the false positive rate of chronic hepatitis in patients with liver cirrhosis, we also found a benign liver disease often accompanied by GPDA-F-positive elevated serum transaminases, suggesting a benign liver disease GPDA-F false-positive inflammatory activity in liver cells. If GPDA-F-positive patients with liver cirrhosis and transaminase elevation was not obvious, to be dynamic observation of PHC could happen. GGH diagnosis of PHC have already been confirmed, 'The results further show that this information will help AFP negative 1I GGT PHC a diagnosis. However, the group C,
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, GT, the positive rate of less than a 1I previous years, reports of cases may be related to sampling error. According to this set of data,
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, GGT Ⅱ diagnostic sensitivity of PHC than GPDA-F, and specific than GH3A-F. PHC serum GGT GPDA-F and a Ⅱ no correlation. indicate that they are complementary diagnosis of PHC. simultaneous determination of these two indicators can be traffic Medicine Volume 14, 2000, 6 the diagnosis of PHC increased to 931% sensitivity, which can reduce the rate of missed diagnosis of PHC. If the two targets at the same time positive, strongly suggests the diagnosis of PHC of PHC diagnostic specificity of 966%. benign liver disease rarely occurs while a GPDA-F and GGT 1I positive. 'In summary, the combined detection of serum GGT GPDA-F and a Ⅱ not only improve the diagnostic sensitivity of the PHC ,
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, but also can improve the diagnostic specificity of the majority of PHC patients, contribute to PHC, especially in the qualitative diagnosis of AFP-negative and the PHC and other benign liver disease,
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, the differential diagnosis of metastatic liver cancer.
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