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MedWire News: Smoking is associated with increased severity of new-onset asthma in allergic adults, research shows.
Writing in the journal Respiratory Research, Riccardo Polosa (University of Catania, Italy) and colleagues observe: "Although factors such as gender Newport cigarettes website, atopy cheap marlboro cigarettes, duration of asthma newport 100's cigarettes, bronchial hyperresponsiveness, and frequent asthma exacerbations appear to be important determinants of the severe asthma phenotype, the association between common modifiable risk factors such as cigarette smoking and asthma severity has received surprisingly little attention."
For the current study newport cigarettes, the researchers examined the influence of smoking on the severity of new-onset asthma among 371 adults with allergic rhinitis who were followed up for 10 years.
Of the 152 patients who developed asthma during follow up cheap Newport cigarettes, 74 (48.7%) were current smokers, 17 (11.2%) were former smokers newport cigarettes, and 61 (40.1%) had never smoked.
Asthma severity among these patients was calculated according to Global Initiative for Asthma criteria and defined as intermittent marlboro lights cigarettes, mild persistent wholesale marlboro cigarettes, moderate persistent, or severe persistent asthma. For the purposes of this study buy newports online, patients with moderate persistent or severe persistent asthma were defined as having severe asthma.
Univariate analysis indicated that current and former smokers had a greater risk for severe new-onset asthma than those who had never smoked, at an odds ratio of 2.10 newport cigarette website, but this became non-significant in multivariate analysis that adjusted for age marlboro red cigarettes, gender wholesale newport 100s cigarettes, family history of atopy, and other factors.
However, pack years of smoking among patients who developed asthma were significantly related to disease severity in multivariate analysis. Indeed, patients with 1-10 cheap newport cigarettes, 11-20 newport cigarettes online, and more than 20 pack-years of smoking were a respective 1.47 marlboro cigarettes stamp, 2.85, and 5.59 times more likely to develop severe asthma than those who had never smoked.