 Wysłany: Pon 16:10, 07 Mar 2011 Temat postu: tory burch reva dtd lug gmj onx |
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| Captopril of bradykinin on neonatal rat cardiac fibroblasts inhibit the proliferation of cells
Part of the role can be antagonistic AnglI:. Recent studies have reported that ACEI is B receptor agonists, can promote JCiinCardioI (China),tory burch reva, Sep2005. Vol21, No9B receptor expression: thus, receptors may be partially mediated the role of ACEI. Ang Ⅱ receptor in turn activated by AT BK / NO pathway,ghd italia, inhibit the development of myocardial fibrosis:, suggesting that NO may be anti-cardiac hypertrophy and myocardial fibrosis plays an important role. NO signal transduction pathway through to generate a negative growth factor in the role of cGMP,mbt shoes italia, which the proliferation of many cells with negative regulatory role. In addition, cGMP may be the BK / NO inhibited the proliferation of CFs part of a cell regulator. CFs in the regulation of proliferation and play an important role:. This study demonstrates that blocking BK by HOE 140, the role of a, the cell culture supernatants and intracellular cGMP No content was significantly lower, indicating that BK-mediated proliferative effect of captopril against CFs generated with NO and cGMP on , which Kim et al: Study conclusions are consistent. In summary, captopril can inhibit the proliferation of CFs,tory burch outlet, the development of cardiac hypertrophy have some reverse effect,adidas scarpe, which might in part by the BK receptor-mediated by the J3, and with the BK / NO / cGMP signaling transduction pathways involved in regulation. However, the specific regulatory mechanisms remains to be further studied. |
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