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. nwaamcefaeffectiveinsuppressingthecontractileresponseevokedby device cIthanthatbyNE. Dipalsoinhibitedthe ~ Cl-indueedcontractioninporcinebasllar,supra shoes outlet, cot '~ retryandradlarteries. TheiznD three valueswere5.7 ± O. 6. 5.4 ± 0.4and4.6 soil 0.5respec- Ya ely. TheselectivityofDipforvasocKiotion fine provedbyhigbpD; valtteofthebastiacarterythanthatofthecoronaryandradialptterles. andthisselectivityofDipwasnlofes ~ lntficantthanthatofCin. Theacuteiv £. Ds0ofDipandCininmicewere37and36mS/kg | ~ ctively. xBYWORDSdipfluzln ~; dnnarizine; thoraciceclrta; has / Jarartery; coronaryvessels; calciumlhannelblockers; vascularsmoothmeseleDipfluzine (Dip) an which diphenylpipera-zinccompound,. wasfirstdevelopedbyDe-[mrtmentofChemistry,herve leger outlet, BeijingUniversity,p90x workout calendar, Chinaaccordingtothecharacteristicsofmblecularformulaofcinnarizine (Cin) andR ~ eived1989Fab2Accepted1989Ag2 head Deim2Unento,jimmy choo wedding shoes, Cl ~ mistry, B state gUn (ver ~. Beiytn8100 & 71,Links of London Charms, Chinadroperido1.0urpreviousstudies <I, hadshownthatDippossessedadosependentdepressiveeffectonbloodDlI called candfemoralres ~ tanoe.andpotentantanistice ~ l InordertoexaminethePh and rmanologicalcharacteristicsofDip, scle ~. tivitie $ onvariousvascular coffee oothmusclepreparationofDipandCinandtheiracutetoxicitywerecomparedinthisPaper.n.c Ldailybeforeuse.ThefMt ~ leconcent good at tiouso who tartaricacidSOlution (0ol and t, pH3.1) |
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