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Sodium nitroprusside treatment of myocardial infarction with dopamine Left Heart Failure Efficacy

【Abstract】 Objective heart failure after myocardial infarction with sodium nitroprusside with dopamine by the positive effect of treatment. Methods 58 patients, 36 patients with acute myocardial infarction (AMI), 22 old myocardial infarction 例 (OMI) in patients with severe heart failure, micro pump infusion of sodium nitroprusside with dopamine 1.0 ~ 3.0 μg / (kg ? min) low-dose infusion,[link widoczny dla zalogowanych], to maintain blood pressure at 90 ~ 120/60 ~ 80 mm Hg between the heart rate, blood pressure and heart function improvement and adverse reactions. Results AMI effective rate was 92.85%, OMI effective rate was 93.75%; the total effective rate was 93.24%. Before and after treatment of blood pressure, heart rate difference was not significant. No case of adverse reactions. Conclusions Nitroprusside dopamine treatment failure after MI, both before and after the heart load reduction, increased myocardial contractility, increasing the cardiac output, efficacy is very satisfactory. � MI Key words after the death of heart failure; nitroprusside; dopamine after myocardial infarction because myocardial necrosis,[link widoczny dla zalogowanych], scar formation and ventricular remodeling, and many other factors,[link widoczny dla zalogowanych], can cause heart failure, if failure is not effectively controlled, will lead to cardiogenic shock, arrhythmia, sudden death, etc., greatly increased mortality after MI. Post-MI heart failure on the active use of the author plus low dose dopamine in the treatment of sodium nitroprusside to obtain satisfactory results, are summarized below. � 1 Materials and Methods � 1.1 General information on 58 cases are from January 2002 to December 2004 inpatients, 30 males and 28 females; combined 46 patients, with diabetes, 17 cases; 36 cases of acute myocardial infarction (AMI), according to WHO 1979 diagnostic criteria was formulated, Killipny function classification were grade III ~ IV; 22 patients with old myocardial infarction (OMI), NYHA cardiac function classification are Class IV by oxygen, cardiac, diuretic, reducing cardiac stress and other measures of clinical symptoms in patients with no significant relief. � 1.2 Method All patients with the highest expansion, anticoagulation, antiplatelet, diuretic, ACEI drugs, aldosterone antagonists, infection control, 6 h thrombolysis within the AMI on the basis of such treatment, of 25 of nitroprusside ~ 50 mg added to 50 ml of normal saline infusion micro pump, started 5 ~ 10 μg / min, according to blood pressure level of 5 ~ 10 min increments every 5 ~ 10 μg, combined with 100 ~ 200 mg of dopamine in normal saline plus or 5% glucose infusion in the infusion pump to 1.0 ~ 3.0 μg / (kg ? min) low-dose infusion to maintain blood pressure at 90 ~ 120/60 ~ 80 mm Hg between the treatment of 5 ~ 7 d . � 1.3 heart rate observed before the project administration, blood pressure, cardiac function by killip record heart function, parallel blood, urine, liver and renal function, myocardial enzymes, electrolytes and other checks; adverse reactions were observed after treatment recorded after treatment 0.5,2,24,48 h heart rate, blood pressure and alleviate symptoms, relief time, record the number of days hospitalized. � 1.4 efficacy evaluation standards to reduce symptoms of chest Bie ease, pulmonary rales, reduced; symptom relief for patients supine standard no complaints of discomfort,[link widoczny dla zalogowanych], pulmonary rales disappeared. The results � 2 � 2.1 AMI improvement of cardiac function group 3 died, were cardiogenic shock; more than 33 cases of discharge killip cardiac function were improved to I level, response rate was 91 .67%. OMI group 2 died,[link widoczny dla zalogowanych], 1 patient died of renal failure, one case of acute respiratory tract infection due to recurrent disease died; more than 20 cases of cardiac function was improved NYHA class I or above, the effective rate of 90.91%. The total effective rate was 91.38 percent. � 2.2 symptom improvement after treatment to alleviate symptoms of the time (1.81 ± 0.75) d. Symptom relief (4.41 ± 1.80) d, and no case of adverse reactions. The average length of stay (13.34 ± 7.43) d. �
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