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 Wysłany: Nie 5:21, 24 Kwi 2011 Temat postu: ghd piastra Parotid 99mTcO-4 dynamic imaging diagn |
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Parotid 99mTcO-4 dynamic imaging diagnosis of Sjogren's syndrome
[Paper Keywords] Sjogren's syndrome; parotid gland; 99mTcO-4 dynamic imaging [Abstract] Objective To study the dynamic imaging of parotid 99mTcO-4 diagnosis of Sjogren's syndrome. Methods Patients with a clinical diagnosis of Sjogren's syndrome in 52 cases (20 cases of primary, secondary 32),[link widoczny dla zalogowanych], normal control group of 25 cases, 40 cases of blood or connective tissue disease, respectively parotid 99mTcO-4 load dynamic imaging of Vitamin C testing,[link widoczny dla zalogowanych], the results of application of the dynamic curve handler Micro Delta semi-quantitative analysis. Results parotid secretion and normal control group, all the normal excretory function, blood or connective tissue disease in the parotid secretion and excretion of group dysfunction in 5 cases. Sjogren's syndrome in 52 cases diagnosed in the parotid gland secretion and excretion of 50 cases of dysfunction, of which 22 cases of bilateral parotid gland does not develop, the rest of the gland can still imaging; its specificity was 92%, sensitivity 96%, Youden index (Youden's index, the correct diagnosis index) of 0.88. Conclusion parotid 99mTcO-4 dynamic imaging examination is simple, non-invasive, safe and accurate for the diagnosis of Sjogren's syndrome provides a good check means. Sjogren's syndrome is a systemic violation of exocrine common connective tissue disease based, dynamic imaging of parotid 99mTcO-4 is the evaluation of salivary gland morphology and function of the ideal means,[link widoczny dla zalogowanych], for drying integrated provide a strong basis for the diagnosis of symptoms. In this study, a parotid gland scintigraphy and time-radioactivity curve in the diagnosis of Sjogren's syndrome application. 1 Materials and Methods 1.1 subjects selected from May 2004 to April 2006 in our hospital diagnosed 52 cases of patients with Sjogren's syndrome (20 primary cases, 32 cases of secondary), diagnosis based on clinical manifestations,[link widoczny dla zalogowanych], combined with SS-A (Sjogren's syndrome A antigen) antibody, labial gland biopsy and other information; choose the same period patient blood or connective tissue disease in 40 patients and normal control group (healthy physical examination and volunteers) simultaneous detection of 25 cases. 1.2 inspection method of subjects intravenous line 370MBq99mTcO-4 peak in the counting device platform,[link widoczny dla zalogowanych], the patient sublingual tablets Vitamin C 300 mg, 64 ĄÁ 64 matrix acquisition a total of 30. The dynamic curve with Micro Delta processing, respectively, after reconstruction of the image superimposed on both sides of the parotid gland and the outline of the end of the ROI, time to get both sides of a radioactivity curve. 1.3 normal results of diagnostic criteria of bilateral parotid images show clear regression of vitamin C stimulated the rapid development and time-radioactivity curve of a significant section of the intake and excretion. Imaging of abnormal results for the parotid gland after stimulation with fuzzy or vitamin C less regression, time-radioactivity curve was a horizontal or low-type, parabolic type, or continue to rise.
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