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Dołączył: 03 Mar 2011
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 Wysłany: Czw 4:27, 17 Mar 2011 Temat postu: adidas scarpe tmn kne fjm thh |
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Verapamil sustained-release tablets Medication Guide
Energy. (4) in the diagnosis of interference: ECG P-R interval in concentrations of 30ng/ml may be extended, is proportional to the degree of blood concentration; QRS time Q-T interval did not change; can transaminase, alkaline phosphatase increased; may lower blood pressure; total serum calcium concentration is not affected. 9 Verapamil interaction with other drugs verapamil 9.1B and B receptor blocker combination therapy of adrenal blockers, can slow down the heart rate produced. For hypertensive patients, the risk of combination therapy may outweigh the benefits, so be careful when combination therapy and intensive care. 9.2 digitalis digitalis drugs verapamil and digoxin in combination drugs such as medication, in the first week of treatment can increase plasma levels of digoxin 50% to 70%. Therefore, when the drugs verapamil, used in combination with digitalis, the need for intensive care patients, if side effects occur,[link widoczny dla zalogowanych], dosage must be reduced or discontinued. 9.3 Other anti-hypertension drug verapamil and other oral anti-hypertensive drugs (such as vasodilation type drugs, angiotensin converting enzyme inhibitors,[link widoczny dla zalogowanych], diuretics, B a blocker) combined for lower blood pressure There will be a good stack effect, patients receiving this combination therapy requires proper conduct of the guardianship, / b, tl, adjust the dose to avoid hypotension. Verapamil decreased adrenal function and combination of drugs can lower blood pressure. 9.4 antiarrhythmic drugs (1) Dual isopropyl pyrazole amines (different pulse stop): Verapamil in the given 48 hours before and after administration should not be given within 24 hours of double-isopropyl pyrazole amine. (2) Flecainide: a study in healthy volunteers, flecainide and verapamil combination therapy on myocardial contractility, AV conduction and depolarization are superimposed, combined medication can cause decreased myocardial contractility and the Housing the extension of ventricular conduction. (3) quinidine: with left ventricular hypertrophy on the small-scale population studies have shown that verapamil and quinidine combination therapy will increase the plasma concentrations of quinidine, resulting in severe orthostatic hypotension and should be avoided. 1O major side effects with conventional therapeutic doses of verapamil,[link widoczny dla zalogowanych], no serious heart failure, hypotension, elevated liver enzymes,[link widoczny dla zalogowanych], AV block and ventricular response so fast side. The statistics, 4,954 cases of verapamil with conventional therapeutic doses in patients with 1. O% or so of the following side effects were: constipation (7.3%); fatigue (1.7%); dizziness (3.3%); headache (2.2%); nausea (2.7%); hot flashes (0.6%); rash (1.2%); bradycardia (hypotension (2.5%); pulmonary edema (1.8%); total AV block (I, Ⅱ, Ⅲ degree) 1.2%; lI, HI degree block (0.8%). 11 acute cardiovascular side effects of acute cardiovascular adverse reactions are rare, so the handling experience is limited. Patients with serious side effects to be observed in the hospital for 48 hours. Cardiac arrest, CPR must be implemented. 12, and dosage should be standard dose prescription medication, tablets should not be chewed, the entire piece with a small amount of water delivery service, it is best to take a short time after dinner, daily breakfast, after a (120mg / piece) the gradual adjustment to the appropriate dose, if necessary, the dose can be increased gradually to two weeks to the day 240rag (1 tablet after breakfast, after dinner, a). Daily dose in patients with long-term medication should not be more than 480mg, for a temporary increase in the dose must be adjusted under the guidance of doctors. For patients with impaired liver function, because metabolism of verapamil in the liver are affected and half-life extension,[link widoczny dla zalogowanych], the extent depending on the severity of liver disease, these patients should be started in small doses, and pay attention to strengthening its observation.
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